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Due to the constriction of the inferior alveolar nerve as it passes through the mandible foramen on is way to the tongue, there is only limited combination of sounds that a human can make. For example, it is physically impossible to pronounce the words "eye", "laws", "dug" and "aim" in sequence. Crazy eh!
Did you know that DCI Gene Hunt's actual first name is Isaac and that his sister, after a recent sex-change owing to unwanted male attention, has changed her name to Mike? True.