Antidepressants not doing anything.
26 February 2008, 09:11 PM
#1
Antidepressants not doing anything.
It has been reported today that antidepressants like Prozac and Seroxat don't actually do anything. Surely even if they are offering nothing more than a placebo effect they are still a viable medication. Scaremongering like this is hardly going to help those who suffer depression and anxiety.
26 February 2008, 09:17 PM
#4
It has been reported today that antidepressants like Prozac and Seroxat don't actually do anything. Surely even if they are offering nothing more than a placebo effect they are still a viable medication. Scaremongering like this is hardly going to help those who suffer depression and anxiety.
26 February 2008, 09:18 PM
#5
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I am soooo depressed at that news .............
Dave
PS: it was said that the placebos had the same effect as the prozac et al. And the placebo effect is well known in this field. I'd get out for a good run myself. My view - *most* *depressed* people should get their ***** off the couch and get some aerobic exercise. Stress is the bodies way of preparing for 'fight or flight' - but if neither occurs then you have big trouble.
PPS: the study also said that the drugs did work for those really really really depressed!
Dave
PS: it was said that the placebos had the same effect as the prozac et al. And the placebo effect is well known in this field. I'd get out for a good run myself. My view - *most* *depressed* people should get their ***** off the couch and get some aerobic exercise. Stress is the bodies way of preparing for 'fight or flight' - but if neither occurs then you have big trouble.
PPS: the study also said that the drugs did work for those really really really depressed!
26 February 2008, 09:19 PM
#7
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It has been proved in studies that anti-depressnts have little real effect. One control group were given placebo and showed remarkable signs of 'recovery', but once told of the deception rapidly declined.
Just goes to show that most depressed people should just pull themselves together!
Geezer
Just goes to show that most depressed people should just pull themselves together!
Geezer
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26 February 2008, 09:23 PM
#10
I am soooo depressed at that news .............
Dave
PS: it was said that the placebos had the same effect as the prozac et al. And the placebo effect is well known in this field. I'd get out for a good run myself. My view - *most* *depressed* people should get their ***** off the couch and get some aerobic exercise. Stress is the bodies way of preparing for 'fight or flight' - but if neither occurs then you have big trouble.
PPS: the study also said that the drugs did work for those really really really depressed!
Dave
PS: it was said that the placebos had the same effect as the prozac et al. And the placebo effect is well known in this field. I'd get out for a good run myself. My view - *most* *depressed* people should get their ***** off the couch and get some aerobic exercise. Stress is the bodies way of preparing for 'fight or flight' - but if neither occurs then you have big trouble.
PPS: the study also said that the drugs did work for those really really really depressed!
26 February 2008, 09:26 PM
#11
It has been proved in studies that anti-depressnts have little real effect. One control group were given placebo and showed remarkable signs of 'recovery', but once told of the deception rapidly declined.
Just goes to show that most depressed people should just pull themselves together!
Geezer
Just goes to show that most depressed people should just pull themselves together!
Geezer
Infact a mate of mine a while back was in a quandry. His wife was a bit of drinker when they went out and it was costing him a fortune. One day he told the barman to give her shots of water after the first couple of drinks. Result she was legless just the same as she would have been after drinking alcohol all night.
26 February 2008, 09:27 PM
#12
My Aunty suffers from depression, and although I don't know the full ins and outs of her treatment, I know she has been put on tablets, and recently the doseage has been increased, but they are having no effect. So unfortunately for her the placeboeffect isn't even working, never mind the drugs themselves.
I'm by far no expert on depression, but I think half the problem is, for as long as I can remember, certain drugs are handed out like smarties, without doctors possibly knowing for sure whether someone is in fact depressed, or if they are, what type of depression it is. Maybe more time needs to be given into finding the root causes of depression, or identifying whether someone is in fact depressed rather than just sending them away with a bunch of tablets.
I'm by far no expert on depression, but I think half the problem is, for as long as I can remember, certain drugs are handed out like smarties, without doctors possibly knowing for sure whether someone is in fact depressed, or if they are, what type of depression it is. Maybe more time needs to be given into finding the root causes of depression, or identifying whether someone is in fact depressed rather than just sending them away with a bunch of tablets.
26 February 2008, 09:32 PM
#13
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Depression is a terrible thing - to those watching someone with depression it is so simple to see what positive things the depressed person should be thankful for - but that doesn't help the depressed person.
Some people are also vulnerable to depression ..... it depends if they see a problem as an opportunity or a set back.
Some people are also vulnerable to depression ..... it depends if they see a problem as an opportunity or a set back.
26 February 2008, 09:43 PM
#16
Depression is a terrible thing - to those watching someone with depression it is so simple to see what positive things the depressed person should be thankful for - but that doesn't help the depressed person.
Some people are also vulnerable to depression ..... it depends if they see a problem as an opportunity or a set back.
Some people are also vulnerable to depression ..... it depends if they see a problem as an opportunity or a set back.
This is exactly the reason I think it needs to be understood more, and doctors need to put more into getting to root causes, than solving the symptoms with tablets.
26 February 2008, 09:53 PM
#20
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the report actually says that some people do not respond to anti depressants.
this is no different to any drug prescribed.
depression is a killer, many people commit suicide, some even do this due to the effects of drugs they are taking, but to say they do not work on everyone is just scaremongering.
i am pretty sure that if you did a study of everyone being prescribed, the effects of the majority on the right drug is beneficial.
some gp's do go through a few differing ones before finding the right one.
the placebo effect has also been found to have flaws as well.
the trouble with a lot of these studies are that they are not always truly independant.
next week a study will show that antidepressants are the cure all, as prozac was when first released.
this is no different to any drug prescribed.
depression is a killer, many people commit suicide, some even do this due to the effects of drugs they are taking, but to say they do not work on everyone is just scaremongering.
i am pretty sure that if you did a study of everyone being prescribed, the effects of the majority on the right drug is beneficial.
some gp's do go through a few differing ones before finding the right one.
the placebo effect has also been found to have flaws as well.
the trouble with a lot of these studies are that they are not always truly independant.
next week a study will show that antidepressants are the cure all, as prozac was when first released.
26 February 2008, 09:53 PM
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26 February 2008, 10:10 PM
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The media reported that anti-depressants don't work, the study said that there was no statistical difference between the drugs tested v placebo (which both worked to varying degrees)
Having worked in drug research for over 10 years, I take the results of such studies with a huge pinch of salt.
Without getting tecchy, these studies that combine data from several studies can often throw up news grabbing headlines. The whole issue of MMR v separate injections is a classic case in point)
The 'problem' with measuring efficacy with respect to such drugs is what measuring tool do you use for the measure in the improvement of symptoms? It's not like a study looking at blood pressure where you can see a definite response or non-response to therapy. For such studies, you need qualitative analysis (often in the form of scales or questionnaires) which though validated are open to the skew effects of subjectivity.
Having worked in drug research for over 10 years, I take the results of such studies with a huge pinch of salt.
Without getting tecchy, these studies that combine data from several studies can often throw up news grabbing headlines. The whole issue of MMR v separate injections is a classic case in point)
The 'problem' with measuring efficacy with respect to such drugs is what measuring tool do you use for the measure in the improvement of symptoms? It's not like a study looking at blood pressure where you can see a definite response or non-response to therapy. For such studies, you need qualitative analysis (often in the form of scales or questionnaires) which though validated are open to the skew effects of subjectivity.
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