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Old 16 June 2005, 02:29 PM
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urban
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Default Any doctors/surgeons on here?

Folks,

As it says I need to get some pointers form a good doctor or surgeon regarding what can happen when someone is administered a drug called "Librium"

Post on here, or take off line, I don't really mind.....But I will take it off line if I go into specific details.
I'm sure you'll understand.

Thanks,

Shaun
Old 16 June 2005, 02:35 PM
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OllyK
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I would be surprised if any medical person would be prepared to say too much without a proper consultation - however you may find a pharmacopeia useful. I found an entry for the drug mentioned here. It is a US website, but it shoudl still apply.
Old 16 June 2005, 03:09 PM
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Sammy Speakeasy
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You need to find out why the patient was given the drug. It is licensed as an anxiolytic, which means it is used to treat anxiety symptoms, but more commonly is used to prevent patients from going into the DTs when detoxing from alcohol.

The main side effect includes drowsiness (if too much is taken).

Short term use only.
A reducing dose is normally prescribed and follow-up for the patient should be arranged.

Librium is the brand name, its generic name is Chlordiazepoxide.
Old 16 June 2005, 03:17 PM
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Taken from a basic teaching package I wrote for students

Anxiolytics (Anti-anxiety)

There are several different types of medications used to help control the effects of anxiety. Despite this we will concentrate on one family of medications known as Benzodiazapines. A certain amount of stress can be beneficial providing a stimulus to action. Too much can lead to anxiety which could be described as fear/apprehension not caused by real danger. Benzodiazapines work by depressing the activity within the brain by promoting the effect of the neurotransmitter Gamma-aminobutyric Acid (GABA). GABA usually blocks the transmission of impulses and therefore the communication within the brain, Benzodiazapines increase the effects of GABA on brain cells that help reduce brain activity that causes anxiety. Some types are also used help insomnia (Hypnotics). These are usually given as tablets, liquids and by intramuscular injection.

Common Benzodiazapines include;
Diazapam – Valium
Lorazepam – lorazepam
Chlordiazepoxide – Librium
Temazepam – Temazepam (hypnotic)
Nitrazepam – Nitrazepam (hypnotic)

Side effects and related problems

There are several reported side effects with Benzodiazapines which include dizziness and forgetfulness. Other report effects include those associated with Antidepressants but they are general well received. The problem associated with Benzodiazapines is the addictive properties of the drug due to sedative effect they can induce. They should be used in the smallest dose for the shortest length of time. The body quickly becomes tolerant to the effects and therefore, to receive any benefit, the dose has to be increased. Dependency is usually found in patients with a history of drug and alcohol problems. Stopping Benzodiazapines suddenly can also lead to withdrawal effects which include excessive anxiety and restlessness.

On the ward we use it as an anxiolytic and alcohol withdrawal.
Due to new guidelines they are supposed to be used in limited amounts nowadays.
Old 16 June 2005, 04:17 PM
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urban
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Originally Posted by richiewong
On the ward we use it as an anxiolytic and alcohol withdrawal.
Due to new guidelines they are supposed to be used in limited amounts nowadays.
And it was being used for alcohol withdrawal, however it proved to be fatal.

From what I understand from basically the consultant (and I won't go into to much), the consultant gave a doseage of this stuff (by vein) which puts you to sleep, and the nurses are meant to give an antidote to wake you up again.
It appears to be that the nurses didn't give enough antidote?

I'm not looking for bashing evidence in this thread,more so a better understanding in lay mans terms that I can understand and relate to easier.

Thanks,

Shaun
Old 16 June 2005, 04:37 PM
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SiPie
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link to Mental Health.com

Urban

This link contains some good info.
Old 16 June 2005, 04:42 PM
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Sammy Speakeasy
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See also:

http://www.inchem.org/documents/pims...te%20treatment

under the heading "10.5 Antidote Treatment".
Old 16 June 2005, 05:30 PM
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GarethE
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Post removed by GarethE - I made an insensitive remark without reading the full thread,

Shaun you have PM

Gareth

Last edited by GarethE; 16 June 2005 at 06:36 PM. Reason: gross insensitivity, sincere apologies
Old 16 June 2005, 05:52 PM
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urban
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Originally Posted by GarethE
Urban, hope the answers have been helpful, I'm afraid I can't offer any advice - but on a lighter note, richiewong must take the award for the most "z" s used in an SN post - congratulations.....

PS...read your post three times, still haven't the remotest idea what you're talking about..
Gareth,

You've got a PM.

Shaun
Old 16 June 2005, 05:56 PM
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urban
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Oops,Didn't meanto send to you....doesn't matter.

Richie, you've got a PM instead.

Plus I'm going home now anyway, read more of this tomorrow.
Old 16 June 2005, 06:38 PM
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Shaun you have PM

Gareth
Old 17 June 2005, 03:11 PM
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this is commonly given in singles to people afraid of flying i believe




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