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Old 23 May 2009, 01:41 PM
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David Lock
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Question Nauseous reaction to anti-Malaria drugs

My daughter is currently traipsing around S America for a couple of months and takes a daily dose of anti-malaria stuff as prescribed by her GP. Specifically 100 mg per day of Doxycycline capsules.

She tells me that they make her feel very nauseous for 2 - 3 hours afterwards which takes the edge off her day.

Any travellers here (not pikeys!) that have used this drug and did it have a similar effect? Any suggestions?

I have checked the product info but not a lot of help. GP is away until Tuesday and pharmacist hasn't a clue.

Not the end of the world but any sensible observations are invited. She is not taking any other medication that I am aware of.

David

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Old 23 May 2009, 01:57 PM
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The Zohan
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is she drinking alcohol?
Old 23 May 2009, 05:37 PM
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tarmac terror
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David, I am still taking 100 mg per day of Doxycycline after my trip to Borneo. How long has she been taking them? I felt slightly ill for the first week, but found that adjusting the time of day when I took them helped. We took them in the afternoon with lunch instead of first thing in the morning. Also make sure to take plenty of water with them (from a bottle not a tap).

If she likes the sun, double up on the sun protection factor, those drugs can make you more prone to burning in the sun.

Best advice will be from GP
Old 23 May 2009, 06:22 PM
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David Lock
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Thank you very much indeed for above helpful comments and I will, of course, try and speak to her GP next week.

To answer some of the points. Having seen a couple of ex-pats in Nigeria with a bout of malaria there is no way I would advise her to take a chance and forget the medication.

I expect she takes the tablets in the morning with plenty of water and yes she does drink but not with her cornflakes!!

She has only been away for a week so early days and perhaps things will settle down.

Thanks again. David
Old 23 May 2009, 08:23 PM
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Gin and Tonic, might be a good substitute!
Old 23 May 2009, 08:27 PM
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David Lock
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Originally Posted by Janspeed
Gin and Tonic, might be a good substitute!
Ah the old Quinine

Kept the Empire going in India for a while

dl

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Old 29 May 2009, 08:00 PM
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David Lock
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Originally Posted by Nat21

Nat, that is a rather stupid and irresponsible comment. You have no idea what you are talking about.

Nowhere does it say the drugs don't work anymore, rather that they may not be as effective as they were.

Granted this is a major blow to anti-malarial prevention. One problem being that ant-malaria research does not attract the big bucks like Aids stuff.

dl
Old 29 May 2009, 08:15 PM
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Malaria - Bill & Melinda Gates Foundation
Old 29 May 2009, 09:03 PM
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David - those sorts of reactions are very common across pretty much the whole range of anti-malarials. Personally I've never suffered when I've been on them apart from the odd crazy dream after my once weekly tablet.

I can suggest that she takes it with breakfast if she's not already - taking them on an empty stomach is generally a sure way of making yourself feel ill. Other than that, there are alternative prophylaxis out there if they are really making her feel that bad.
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